Chiral chromatography

by Thomas E. Beesley

Chiral Chromatography provides the reader with a basic understanding of the nature of chromatographic separations and relates the principles specifically to the separation of enantiomers. The following information is included: chiral separations involving both gas and liquid chromatography, descriptions of the apparatus used for both techniques, detailed discussion on the retention mechanism that results in chiral selectivity, the structure and synthesis of a wide range of chirally active stationary phases used in both gas and liquid chromatography, preparative applications for large scale purification of enantiomers, and applications of capillary electrophoresis and capillary electrochromatography. In addition to the above, a large number of examples of the separation of both commercially and physiologically interesting chiral mixtures are given, as is a detailed discussion on the mechanism of selectivity of each example.